Asian subjects with T2D had significantly lower tissue compositions of C22:6n-3 (SMD: -1.43 95% CI: -1.75, -1.12) and total n-3 PUFA (SMD: -1.41 95% CI: -2.23, -0.59) compared with those without T2D. Subgroup analyses indicated that summary RR (highest vs lowest category) of T2D for fish and marine n-3 PUFA intake was 0.89 (95% CI: 0.81, 0.98) and 0.87 (95% CI: 0.79, 0.96) for Asian populations, and 1.20 (95% CI: 1.01, 1.44) and 1.16 (95% CI: 1.04, 1.28) for Western populations. For cohort studies, the summary RR of T2D for the highest vs lowest categories of total fish, marine n-3 PUFA and alpha-linolenic acid intake was 1.07 (95% CI: 0.91, 1.25), 1.07 (95% CI: 0.95, 1.20) and 0.93 (95% CI: 0.81, 1.07), respectively. Twenty-four studies including 24,509 T2D patients and 545,275 participants were identified. Random-effects models were used to pool the summary relative risk (RR). Two authors independently extracted the data. PubMed, Embase, Cochrane library, China National Knowledge Infrastructure (CNKI) and Chinese VIP database up to January 2012 was used to identify relevant studies, and reference lists from retrieved studies were reviewed. The differences in tissue n-3 PUFA compositions in subjects with and without T2D were investigated based on cohort and case-control studies. We conducted a systematic review and meta-analysis of prospective cohort studies to examine the associations of fish and n-3 PUFA intake with T2D risk. Differences in tissue n-3 PUFA compositions in subjects with and without T2D were also inconsistent in both cohort and case-control studies. It’s also a good exercise in being careful about the words you use online-never a bad thing to brush up on.Prospective cohort studies in relation to the associations between n-3 polyunsaturated fatty acids (PUFA) and risk of type 2 diabetes (T2D) were inconsistent. It’s an otherwise fun experience that adds a neat twist to mundane, everyday conversations about what you want on your pizza. Hopefully, Blot intends to iron out Chat Fu‘s wrinkle. Depending on your screen resolution, you may wind up dealing with three scrollbars at once, which is a huge inconvenience when you’re trying to type and keep stock of your trap words.
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However, Chat Fu is in desperate need of a full screen mode. You can also engage multiple chat partners at once if you’re in the mood to get intense. It adds a humorous sense of urgency to normal interactions. It’s fun to watch your onscreen guys flail at each other while you carry on a conversation about going out for pizza. It takes skill to carry on a normal conversation with a friend while steering him or her away from, or towards, certain words. It’s mega-challenging (and maybe a little creepy) to play the game with an opponent who’s not aware that he or she is actually playing a word game with you. It’s easy to appreciate the creative spins that Chat Fu puts on the standard Charades formula. So it should definitely be a last resort). If things get too hairy for you, you can simply give up (the game’s instructions make it clear that if you take this route, you will feel shame. You can also buy ninja stars that let you disarm trap words, or change out your target word entirely. Coins spill out when you make successful hits, which you can use to buy more fighters. The idea is to get your friend to say a word that’s related to the category, but you can’t use any of the listed “trap words.” If you use a trap word, you lose.įor instance, you might choose “Pop Culture” and be instructed to make your pal type “Facebook”-but you’re forbidden from using words like “Wall” or “Social Media.” You can simply ask your friend, “Say, what platform are we chatting on right now?” If you’re lucky, he or she will type, “Uh, Facebook?” If you’re not lucky, your answer might be, “What are you stupid or something?”Īs you and your buddy type, the dudes on-screen will trade blows. You choose a friend to spar with, and select “Fight.” Then you pick a category: some selections include Pop Culture, Food, TV, and Cartoons. The game runs through Facebook’s chat function. So is your opponent, although he or she doesn’t realize it. Chat Fu for Facebook offers a good time with words and flying fists, even if there are some technical issues that foul up the fight a bit. The game plays like an action/fighting title that’s been cross-bred with Charades. Chat Fu by Blot Interactive drives home a point we all learned in grade school: words can hurt.
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